National Vaccine Injury Compensation Program | HRSA

Most people are not aware of Compensation packages for victims of Covid vaccination complications.

The federal government and the media have been lax in announcements of this safety net.

Much controversy still exists regarding the side effects of COVID-19 vaccinations and booster injections. Numerous complications have occurred, including Long Covid, Myocarditis, Pericarditis, Anaphylaxis,  and Guillan Barre Syndrome

For claims associated with the COVID-19 vaccine or other COVID-19-related countermeasures, please file your Request for Benefits with the Countermeasures Injury Compensation Program.

In the rare chance you suffered a serious injury, or the death of a loved one, from the administration or use of a covered countermeasure, you may be eligible to file a claim for benefits.

You must file a Request for Benefits Package within one year of receiving or using the countermeasure that you believe caused the injury. You must also provide proof that a covered countermeasure was administered or used.

Learn more about the criteria for demonstrating that a covered injury occurred.

How To Apply for the Victim's Compensation Fund for Covid Vaccination complications. (ONLINE)

Claimants will need to file relevant medical records (hospital, physician records, laboratory, and imaging records.

The National Vaccine Injury Compensation Program (VICP) is a no-fault alternative to the traditional legal system for resolving vaccine injury petitions. The VICP provides compensation for people injured by certain vaccines.

Any individual, of any age, who received a covered vaccine and believe they were injured as a result, can file a petition. Parents, legal guardians and legal representatives can file on behalf of children, disabled adults, and individuals who are deceased.

How to submit a petition with the U.S. Court of Federal Claims

Your petition must be filed with the U.S. Court of Federal Claims.

Submit your petition, one original and two copies, including cover sheet, medical records, and other documentation plus the appropriate filing fee to:

Clerk

U.S. Court of Federal Claims

717 Madison Place NW

Washington, DC 20439

The fees are considerable

The process is complex and may take considerable time to obtain relief. The vaccine compensation fund has been in existence for some time and originally covered reactions to childhood immunizations.

After you submit your petition to the U.S. Court of Federal Claims, you can log in into this system and submit a copy of the petition to HHS.

If you are unable to pay the filing fee, call 202-357-6400.

OSM fee allowances  Because this amounts to filing a lawsuit with the federal government, a successful claim includes a payment to an attorney who represents you.

There is a one-year limit for filing a claim, and it is important to file a letter of intent if you cannot obtain all the documentation prior to the one-year statute of limitations

COVID-19 Vaccine Cross-Border Liability and Compensation

National Vaccine Injury Compensation Program | HRSA

I just tested this VR meditation app on Meta Quest 2 — and it blew my mind | Tom's Guide

If you like to meditate or are looking for a guide, check this out.

This is a form of guided meditation. It is immersive in auditory and visual stimuli. You are able to choose a variety of settings.

Virtual reality has matured into a format that is affordable. Many companies offer VR headsets.

 

Virtual Reality Companies,  Hardware, and Software

Explore the top Virtual Reality Companies with their core services and ratings to select the best VR Company per your requirements:

This VR tutorial discusses the top and popular virtual reality companies by rating, popularity, and amount of projects or value of projects undertaken.

Virtual reality companies are gathering pace in the industry despite being a relatively new field for them.

In most cases, the industry favors those invested highly in other technologies such as gaming, the Internet, and computing. Thus we have the likes of Microsoft, Google, AMD, NVIDIA, and Samsung.

This does not mean we do not have start-ups that have stolen the show, including the likes of Oculus VR, Next/Now, and Magic Leap, some of which started with public crowd-funding rounds.

Market Trends:

48% of consumers prefer to buy from a retailer using VR and AR experiences for marketing and branding.

32% of retailers are planning to deploy virtual and augmented reality applications in the next three years, according to the research linked above.

North America will lead in the adoption of VR by companies, with Europe leading in the automotive industry implementation of VR as per the above research. Competition is intensifying among players and the biggest VR companies, as most expand their R&D in VR.

Expert Advice:

For a brand looking to integrate or start using virtual reality technology, you want VR tech companies already established in the VR tech you are looking for. Example: Working with a VR headset manufacturer to brand your headsets or with a studio to produce branded VR experiences for your customers.

In the list, we have VR companies dabbling in consultancy as well as that manufacturing hardware for VR. For instance, you might be a hospital or medical institution that wants to use VR for remote and immersive training of doctors. You might need a company that will handle both manufacturing of hardware such as VR headsets and at the same time produce and customize your customer’s VR experiences.

If you want to come up with a VR app or design a VR experience, the best virtual reality companies are those studios dealing in the actual field in which you need help like producing VR-branded experiences in healthcare or education. Nevertheless, most should be able to help regardless of the industry.

For a group or company or individual looking for a company to invest in, the most promising and best virtual reality companies invest in day-to-day uses of VR like in gaming, healthcare, education, marketing, branding, and social life.

I just tested this VR meditation app on Meta Quest 2 — and it blew my mind | Tom's Guide

Cancer vaccine trials to begin in Britain this year

Cancer vaccine trials will start in the UK this year after the Government signed a deal with BioNTech, the company that created the mRNA technology behind the Pfizer Covid jab.

This is another advancement based on science from the 1960s- 2000.

In fact, the mRNA vaccine platform from BioNTech was first developed and tested in humans initially as an experimental cancer vaccine as far back as 2008, when 13 melanoma patients were vaccinated using the mRNA platform.

When they were vaccinated, the immune system’s reactivity against tumors did become elevated, the researchers reported. And as a result, their risk of developing new metastatic lesions was significantly reduced. Moderna’s cancer mRNA vaccine, which takes a different approach, similarly induced an immune response in solid tumors — work that also began years ago. And when they combined it with a checkpoint inhibitor, the therapy shrank tumors in six out of 20 patients.

'Redemption': How a scientist's unwavering belief in mRNA gave the world a Covid-19 vaccine. For Katalin Karikó, vaccine approval is a validation of 40 years of hard work and opens the door to a new generation of medicines

Will her work bear fruit for cancer vaccines? Unlike the Moderna Biontech Covid vaccine, a cancer vaccine does not prevent cancer. Cancer vaccines will be used to treat otherwise untreatable cancers or as an adjunctive treatment.

The agreement will enable BioNTech to conduct cutting-edge clinical trials, with British patients set to be enrolled as soon as autumn. The so-called cancer vaccines are not preventative but are therapeutic tools designed to fight established diseases and advanced tumors.

BioNTech created the world’s first authorized mRNA vaccine for Covid in 2020, which works by injecting a person with a small piece of genetic code to create a specific immune response.

Multiple forms of cancer, including breast, lung, and pancreatic, will be targeted by BioNTech’s vaccine technology, as well as Covid, malaria, and TB. “The collaboration will cover various cancer types and infectious diseases affecting collectively hundreds of millions of people worldwide.  Data published last year and presented at a conference in Chicago showed that in eight of 16 people with pancreatic cancer, a custom immune response was created to target their tumor with nine doses of the cancer vaccine, each given a week apart.  

What is the new Cancer Vaccine?   Is it safe for people with cancer to be vaccinated with Moderna vaccine? 

How mRNA Vaccines Help Fight Cancer Tumors

Protection vs. Attack

There’s a key difference between how a vaccine would be used to treat cancers versus a vaccine that’s used for an infectious disease like COVID-19.

First, the mRNA vaccines for COVID-19 protect people from the virus. They’re prophylactic. But a cancer mRNA vaccine is an intervention (a treatment) given to patients with the hope that their immune systems would be activated in a way that would attack tumor cells.

Through their research, Pardi and others, including researchers whose work led to the development of the BioNTech and Moderna vaccines, Drew Weissman, MD, PhD, a professor of Infectious Diseases in the Perelman School of Medicine, and Katalin Karikó, PhD, an adjunct associate professor at Penn and a senior vice president at BioNTech, found that mRNA vaccines can not only prompt strong antibody responses to fight off invaders, like COVID-19, but also potent cytotoxic T cell responses.

That’s important because these T cells can kill cancer cells. They just need to be altered or motivated to do it. Think immunotherapy, like checkpoint inhibitors or chimeric antigen receptor (CAR) T cell therapy that engineers a patient’s own T cells to find and destroy cancer cells.

“A successful therapeutic cancer vaccine should induce strong T cell responses, particularly with CD8+ T cells, which have a known capacity to kill malignant cells,” said Pardi, who is currently leading studies to better understand mRNA vaccines to treat cancers, along with other diseases. Pardi was also a postdoctoral researcher in Weissman’s lab and a frequent collaborator with him and Karikó. “Therapeutic cancer vaccines would be given to cancer patients with the hope that those vaccine-induced cytotoxic T cells would clear tumor cells.”

One example is an mRNA vaccine that targets proteins called neoantigens on a tumor to fight it. A neoantigen is a new protein that forms on cancer cells when certain mutations occur in tumor DNA.

“It’s a promising group of cancer antigens to keep exploring,” Pardi said.

This brings us to "Precision Medicine"

According to the Precision Medicine Initiative, precision medicine is "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person." This approach will allow doctors and researchers to predict more accurately which treatment and prevention strategies for a particular disease will work in which groups of people. It is in contrast to a one-size-fits-all approach, in which disease treatment and prevention strategies are developed for the average person, with less consideration for the differences between individuals.

Getting Personal

The biggest challenge in developing these types of mRNA vaccines for cancer, though, is just how personal it has to be. The majority of everyone’s tumor neoantigens are specific to them.

It can’t be a catch-all approach like other vaccines — it needs to be personalized, much like CAR T cell therapy, which requires taking a patient’s own T cells, engineering them to seek out a specific antigen on a tumor cell, and then infusing them back in to find and kill them.

“That’s why we need a vaccine technology that is flexible and potent, such as the mRNA technology used for COVID-19,” Pardi said. “It could be developed to give us personalized neoantigen vaccines.”

A similar vaccine for metastatic prostate cancer known as sipuleucel-T (Provenge) stimulates an immune response to prostatic acid phosphatase, or PAP, an antigen present on most prostate cancers. While it’s not mRNA technology, it is customized for each patient and been shown in clinical trials to increase the survival of men with hormone refractory metastatic prostate cancer by about four months.

So far, it’s the only one approved by the U.S. Food and Drug Administration.

Cancer vaccine trials to begin in Britain this year

Are Drugs Past Expiration Date OK?

Pharmaceutical drugs, both prescription and over-the-counter come with an expiration date. This manufacturer expiration date applies to unopened containers and many patients think they should discard expired meds or that it will be dangerous to take them. But do they really need to toss the "old" one and buy something new?  Is there a problem with safety? What about the efficacy...will it still be potent?

The Medical Letter on Drugs and Therapeutic, a well-respected and non-biased publication, looked at shelf life extension and the stability of expired medications. They showed that all drugs they tested were stable for a year past the expiration date, and most drugs stored in unopened original containers were fine for 66 months. (that's 5 years!) One drug, theophylline retained 90% of its potency 30 years past its expiration date. 

Solutions and suspensions are less stable than solid medications. Epi-Pen auto-injectors may lose potency after the expiration date so that is one that should be replaced if expired.

So the answer to the above questions about using expired medications are here:

1.  Is there a problem with safety?  No. There are no reports of toxicity.

2.  Will it still be potent?  If the medication is in a cool, dry place in the original container, it is probably 90-100% potent and good for at least a year after expiration and maybe even up to 5 years later. Exceptions would be Epi-Pen, liquid antibiotics, and insulin.

What Is Neurodiversity? - Child Mind Institute

What You'll Learn

• What does the term neurodiversity mean?
• How does the neurodiversity movement, launched in the 1990s, help kids with autism, ADHD, or learning disorders?
• Neurodiversity also helps children cultivate self-esteem, viewing their differences not as impediments but simply as expressions of their uniqueness. As these attitudes are cultivated in children, they become better prepared to handle their neurodivergence in college, in the workplace and throughout their adult lives.Why are teenagers and young adults adopting neurodiversity as an identity?

Lately, neurodiversity has also become an identity sometimes adopted by teenagers who are struggling socially. The concept gives them a brain-based explanation for their difficulties: “I'm like this because my brain works this way.” And it can help them feel connected to others who identify as neurodivergent.

A central premise of the neurodiversity movement is that variations in neurological development and functioning across humans are a natural and valuable part of human variation and therefore not necessarily pathological (e.g., Jaarsma and Welin, 2012; Kapp, 2020)

Neurodiversity is a term that seems to be everywhere these days. And increasingly, kids and young adults are using it to describe themselves. But what does it mean to be neurodiverse, and where does the term come from?

In short, it means that there are many differences in the way people’s brains work. There’s no “correct” or “incorrect” way. Instead, there is a wide range of ways that people perceive and respond to the world, and these differences should be embraced.

The term neurodiversity was coined in the 1990s to fight stigma and promote acceptance of people with autism. But it also includes other conditions that involve neurological differences, such as ADHD and learning disorders like dyslexia and dyscalculia.

Autistic Self-Advocacy and the Neurodiversity Movement: Implications for Autism Early Intervention Research and Practice

The growth of autistic self-advocacy and the neurodiversity movement has brought about new ethical, theoretical, and ideological debates within autism theory, research, and practice.  The last two decades have brought about huge socio-political shifts within the world of autism theory, research, and practice. In the mid-1990s, the emergence of the internet provided a more accessible text-based means of communication and empowered a growing number of autistic people to connect and share ideas with one another (Dekker, 2020)1. Out of the early autistic social groups of the 1990s emerged autistic culture, the autistic self-advocacy movement, and the assertion that autism is a valid way of being. This environment also gave rise to the neurodiversity movement (Singer, 1998). Through the 2000s, the neurodiversity movement has been galvanized in a large part due to the voices, advocacy, and protest of the autistic community, facilitated through developments in online communication and networks (Kras, 2009) and is increasingly influencing academic, clinical, and lay understanding of autism and other forms of neurological difference

A central premise of the neurodiversity movement is that variations in neurological development and functioning across humans are a natural and valuable part of human variation and therefore not necessarily pathological (e.g., Jaarsma and Welin, 2012; Kapp, 2020). Neurodiversity as a social justice and civil rights movement intersects with the wider disability rights movement (Hughes, 2016). The most significant premise of both is that disability is not simply a defect in the individual, but arises from the interaction between a non-standard individual and an unaccommodating environment (the social model of disability; Oliver, 1990). Consistent with this stance, many neurodiversity proponents do view autism as a disability. From this theoretical underpinning, the neurodiversity movement makes several demands, including the recognition and acceptance of the value of cognitive variation as a form of biodiversity and hence its positive contribution to groups, communities and societies (the social-ecological perspective; Chapman, 2020) and equal rights leading to an end to discriminatory policies and practices (Runswick-Cole, 2014).

What Is Neurodiversity? - Child Mind Institute

The impact of using digital mental health apps.

The COVID-19 crisis has uncovered an enduring mental health epidemic globally.

New ethical questions about the safety, efficacy, equity, and sustainability of digital mental healthcare – online and through apps – are being raised around the world, and businesses are being held to account over their creation and endorsement of services.

Over 10,000 mental health apps are currently on the market, yet regulations do not fully protect against the sharing of sensitive consumer data or ensure a standard quality of, for example, chatbot psychologists. Telehealth has contributed to solving the paucity of mental health providers.  This was even more apparent during the COVID pandemic. The pandemic fueled a large uptake in the use of telehealth during the necessity of social distancing. 

Not only is telehealth used for telemedicine there are also numerous mental health apps available for patients.

Best overall: Moodkit

Best for therapy: Talkspace

Best for meditation: Headspace

Best for suicide awareness: Better Stop Suicide

Best for stress: iBreathe

Best for anxiety: MindShift CBT

Best for addiction: Quit That!

Best for boosting your mood: Happify

Best for eating disorders: Recovery Record

Best for OCD: NOCD

Best for sleep: Calm

Best for drinking less alcohol: Reframe

Best for quitting alcohol: I Am Sober

Mental Health the Trillion Dollar Challenge (Spotify)

What’s the challenge?

Between a quarter and half of the global population is affected by a mental disorder at some point in their life. Between 2011 and 2030, the cumulative economic output loss associated with mental disorders is projected to be $16.3 trillion worldwide.

Disruptive technologies – such as artificial intelligence and machine learning, digital reality, blockchain, and the cloud – are ushering in a new era for consumers, industries, and organizations. There are more than 10,000 mental health apps in the Apple App Store and the Google Play Store alone. Many of these 10,000 apps are not currently evidence-based, placing users at significant risk in some cases. Deloitte analyzed 190 global high-traction use cases for the toolkit, revealing 89% of the apps are not clinically validated.

Web 3.0, Virtual Reality, and the Metaverse will also contribute to new online therapies.

Online platforms have the potential to engage patients in a patient-centric manner.

Meditation Virtual Reality

Try Healium

The uptick in VR meditation parallels an avalanche of smartphone apps for mental health, which total about 20,000. VR is more immersive than smartphones and, some say, can enable feelings of awe, relaxation, mindfulness, and connection with fellow meditators— or their avatars, at least

Protecting users of digital mental health apps | World Economic Forum

COVID FACTS. VAERS Summary for COVID-19 Vaccines

VAERS Summary for COVID-19 Vaccines through 12/16/2022

VAERS Summary for COVID-19 Vaccines through 12/23/2022

What will 2023 bring ?

Are we on the verge of another pandemic year ? There are many factors now developing for the United States. Anthony Fauci M.D. has retired from the NIH. His parting advice.......wear a mask

1. China has lifted its strict Zero Covid policy

2. The United States has opened travel from China to the U.S. with certain provisions

Covid vaccination statistics for the U.S.

Are we well prepared for 2023 ?

Dr. Fauci’s Legacy--IT'S EASY TO THROW ROCKS

Dr. Marty Makary writes on the public health risk of putting America’s fate in the hands of one doctor. Dr. Markery himself is no slouch, Dr. Makary is the chief of Islet Transplant Surgery at Johns Hopkins and is the recipient of the Nobility in Science Award from the National Pancreas Foundation. He has been a visiting professor at over 25 medical schools, has published over 250 peer-reviewed scientific articles, and has been elected to the National Academy of Medicine.  A graduate of Bucknell, Thomas Jefferson, and Harvard Universities, he completed his surgical residency at Georgetown University and his specialty training at Johns Hopkins Hospital. is in a position to analyze the Covid 19 debacle. However, I disagree entirely with Dr. Makary's opinion.  

Anthony Fauci was brought into the spotlight by then President Donald Trump in 2020 at the beginning of the COVID pandemic. At times it was obvious he did not agree with Mr Trump's opinions and edicts.

Fauci became the ground zero  for controversy and suffered from overexposure by the media, who were desperate to headline breaking news.  For several years COVID disrupted normal life in America, fueled not so much by Fauci, but by news media.

Video Interview of Anthony Fauci MD

Here, on the last day of 2023 some are casting stones at Anthony Fauci, who today ends a long life of dedication to advising many Presidents, Republican and Democratic..

Perhaps  he should have retired at age 65.  The National Institute of Health does not have a mandatory retirement age. Many scientists have worked their entire lives and are brilliant investigators.  Not only do they research, they also teach and act as mentors to fellows, and medical students, advising others. The NIH has many divisions including Fauci's (the National Institute of Allergy and Infectious Diseases. Most of them only receive an appointment to NIH as gifted scholars after a very competitive application process. Many of them come from prestigious research universities, such as UCLA, Harvard, MIT, They have all demonstrated proficiency in publishing peer reviewed articles while they were. undergraduates, either in college and/or medical school.  Many are combined MD/PhD candidates. Most are still very productive and creative. They mentor younger minds and guide their scientific journey at NIH.

Anthony Fauci's origins at his parents Pharmacy in Bensonhurst, N.Y.

Fauci ascended to a leadership position at NAID over many years. His earliest contributions to science number 336 according to PubMed, the NIH catalog of peer reviewed medical science library.

Dr. Fauci’s Legacy: Dr. Marty Makary on the public health risk of putting America’s fate in the hands of one doctor.

Illegal Fentanyl is the scourge of overdoses by opioids

Contrary to media sources prescriptions for opioids (codeine, hydrocodone) is not the main cause of overdoses in the United States.

Illegal sources of fentanyl (DEA). 

Currently, China remains the primary source of fentanyl and fentanyl-related substances trafficked through international mail and express consignment operations environment, as well as the main source for all fentanyl-related substances trafficked into the United States. Seizures of fentanyl sourced from China average less than one kilogram in weight, and often test above 90 percent concentration of pure fentanyl.

This is how Fentanyl is causing so many deaths.  

Fifty times stronger than heroin, one hundred times stronger than morphine, fentanyl is very dangerous, a quantity like 2 grains of salt can be lethal.

A Tavares, Florida police officer has her coworkers to thank for taking decisive, lifesaving action when she overdosed ...from inhaling fentanyl powder accidentally when doing a traffic stop.

 It was a windy day and even though the officer wore protective gloves when handling the plastic containers of fentanyl powder, it is thought that she inhaled some of the fentanyl powder when the wind blew it into the air.  Fortunately her fellow officers had Narcan (a powerful antidote) readily available. Narcan is administered as a nasal spray.

Public health measures such as:

Establishing a leave behind program enables first responders to leave naloxone kits with the family, friends, or bystanders at the scene of a non-fatal overdose. Survivors are at high risk for repeated overdoses, providing naloxone to these individuals and their loved ones is especially important.

VIDEO: Bodycam Shows Officer Overdosing After Fentanyl Exposure, Fellow Officers Saving Her Life With NARCAN: 

A Comparison of Nurse Practitioners, Physician Assistants, and Primary Care Physicians' Patterns of Practice and Quality of Care in Health Centers - PubMed

Who was that person in the white coat that saw me today in the clinic? Should I have called them 'Doctor'??

For the last several decades what we are calling mid-level practitioners. have been present in a variety of settings.  Various titles have been assigned to them dependent upon which route they took to become mid-level practitioners.  Nurse practitioner, physician assistant.  It is not so straight forward to telling you how advanced their training has been.

M.D.s and D.O.s normally have three or four years of undergraduate degrees leading to a bachelor's degree, followed by four years of medical school and then postgraduate training in a general or specialty area.  Over time this training has evolved and become longer.  Mid-level health personnel may have previously been R.N.s or taken a route to become a physician assistant in special programs. Some P.A.s may also become 'specialty PAs' serving as assistants to surgeons as extenders.

It becomes obvious a long white coat is no longer a beacon called 'doctor'.

This phenomenon has become more prominent due to organizations such as the. Veterans Administration Health System, the Department of Defense and some managed care institutions.  The initial impetus was to increase accessibiliy when physicians are in short supply and/or over worked.  A secondary gain has been some cost savings.  

In all instances the mid level practtiner reports to a licensed physician. They do not practice independently.

: Under the Affordable Care Act, the number and capacity of community health centers (HCs) is growing. Although the majority of HC care is provided by primary care physicians (PCMDs), a growing proportion is delivered by nurse practitioners (NPs) and physician assistants (PAs); yet, little is known about how these clinicians' care compares in this setting.  

 Primary analyses included 23,704 patient visits to 1139 practitioners-a sample representing approximately 30 million patient visits to HCs in the United States.

Measures: We examined 9 patient-level outcomes: 3 quality indicators, 4 service utilization measures, and 2 referral pattern measures.

Results: On 7 of the 9 outcomes studied, no statistically significant differences were detected in NP or PA care compared with PCMD care. On the remaining outcomes, visits to NPs were more likely to receive recommended smoking cessation counseling and more health education/counseling services than visits to PCMDs (P≤0.05). Visits to PAs also received more health education/counseling services than visits to PCMDs (P≤0.01; design-based model only).

Conclusions: Across the outcomes studied, results suggest that NP and PA care were largely comparable to PCMD care in HCs.

A Comparison of Nurse Practitioners, Physician Assistants, and Primary Care Physicians' Patterns of Practice and Quality of Care in Health Centers - PubMed

Practice Environment and Workforce Outcomes of Nurse Practitioners in Community Health Centers

A survey of implicit bias training in physician assistant and nurse practitioner postgraduate fellowship/residency programs

The development of a visual dashboard report to assess physician assistant and nurse practitioner financial and clinical productivity

Factors associated with federally qualified health center financial performance

This study. is highly biased as it only surveys in FQHMCs. (Community Health Centers).  The cohort of patients is almost 100% Medicaid, a statewide payer through a variety of managed care programs such as the Inland Empire Health Plan and Molina Care.

Both of these entities are not for profit plans, paid for entirely by state and federal medicare funds.  These plans reimburse providers and hospitals amounts far below the usual and customary fees.  Hospitals and providers are paid barely their cost to provide services.  They could not exist without indirect subsidies by private payers.

The statistical results as to quality of care may be biased since the study is done by the entities themselves, to justify the use of mid level practitioners.

Nearly 90% of those living with long COVID have not returned to full health

The study of 988 participants conducted by APC Microbiome Ireland, an SFI research center based at University College Cork (UCC), in conjunction with Cork University Hospital (CUH) and long COVID Advocacy Ireland, provides greater insight into impact of long COVID on quality of life, mental health and physical health of people in Ireland. The study is published in HRB Open Research.

More than 2 out of 3 participants continue to experience fatigue, post-exertional malaise, palpitations, chest pain, stomach upset/nausea, memory problems, muscle pain or joint pain. The median number of long COVID symptoms reported was 8 for each person, highlighting the substantial burden of this disease. The median reported time since the initial COVID-19 infection was 12 months

Six out of every ten missed workdays

A high proportion of long COVID patients reported that they still have a moderate to severe limitation in their ability to carry out their usual daily activities. Nearly 4 of 10 people were severely limited in their ability to work and 6 of every 10 have missed workdays (at some stage) due to their long COVID symptoms. 16% of respondents were unable to work at the time of the survey due to long COVID and were receiving social welfare supports.

The survey was produced in a researcher-clinician-patient partnership involving Professor Liam O'Mahony, APC Principal Investigator and UCC Professor of Immunology, Dr. Corinna Sadlier, Consultant in Infectious Diseases at CUH, and Ms. Tanja Buwalda, long COVID sufferer and representative of "Long COVID Advocacy Ireland."

This working group included patient engagement to ensure the survey would impact patients in a targeted and meaningful way, and ultimately help inform care pathways in the treatment of long COVID.

SARS-CoV-2 infection not only impacts the lungs

Professor O'Mahony said, "This survey highlights that SARS-CoV-2 infection not only impacts the lungs but can have significant long-term effects on multiple organ systems following clearance of the acute SARS-CoV-2 infection in many Irish people who were otherwise healthy previously. The reasons why some people develop long COVID, and others do not, are still unclear. While many different biological mechanisms have been proposed, we are focusing on the role of the immune system and the microbiome in these complicated disease processes.

Dr. Corinna Sadlier said, "The study demonstrates the significant and wide-ranging impacts long COVID is having not only on physical health, but also on ability to carry out usual daily activities, return to employment and overall quality of life.Fatigue is the single most frequent symptom reported," Professor O'Mahony continued.  

Ref:

 Liam O' Mahony et al, Impact of Long COVID on health and quality of life, HRB Open Research (2022). DOI: 10.12688/hrbopenres.13516.1

Nearly 90% of those living with long COVID have not returned to full health: 

This Couple Died by Suicide After the DEA Shut Down Their Pain Doctor

“There are millions of chronic pain patients suffering just like me," Danny Elliott wrote before ending his life. "Nobody cares."

DEA, FDA, CDC often overstep their missions.  This is all to common a problem.

Many physicians should push back and be aggressive if confronted by their state medical boards, or other regulatory bodies.  Organized medicine must do more to protect patient rights to access treatment. A referral to a pain specialist may not be adequate protection.  One would think an ethical and properly trained pain medicine physician would escape algorithm care.  Then again there are other means to alleviate pain.  Suicide should not be an option.

It was a Tuesday in early November when federal agents from the Drug Enforcement Administration paid a visit to the office of Dr. David Bockoff, a chronic pain specialist in Beverly Hills. It wasn’t a Hollywood-style raid—there were no shots fired or flash-bang grenades deployed—but the agents left behind a slip of paper that, according to those close to the doctor’s patients, had consequences just as deadly as any shootout.   

On Nov. 1, the DEA suspended Bockoff’s ability to prescribe controlled substances, including powerful opioids such as fentanyl. While illicit fentanyl smuggled across the border by Mexican cartels has fueled a record surge in overdoses in recent years, doctors still use the pharmaceutical version during surgeries and for soothing the most severe types of pain. But amid efforts to shut down so-called “pill mills” and other illegal operations, advocates for pain patients say the DEA has gone too far, overcorrecting to the point that people with legitimate needs are blocked from obtaining the medication they need to live without suffering. 

Starting around 2016, a backlash to prescribing opioids began to spread across the U.S. healthcare system, sparked in part by guidance from the Centers for Disease Control and Prevention (CDC) that prompted scrutiny of patients on doses equivalent to over 90 milligrams of morphine per day. The National Committee for Quality Assurance, which develops quality metrics for the healthcare industry, has implemented its own 90 milligram threshold, and patients over that baseline count as receiving “poor care,” regardless of their dose history. In practice that means doctors have strong incentives to reduce the dosage, even for someone like Elliott, who had been taking the same prescription for years, and even if it’s not necessarily in the best interests of the patient. Since 2018, the CDC has developed an initiative called the Opioid Rapid Response Program, which is supposed to assist when doctors lose the ability to prescribe pain medication. Stephanie Rubel, a health scientist in CDC’s Injury Center who leads the program, said when the DEA visited Bockoff’s office, “a healthcare professional was onsite in case any patients arrived for their appointments.”

One of Bockoff’s patients who relied on fentanyl was Danny Elliott, a 61-year-old native of Warner Robins, Georgia.

This Couple Died by Suicide After the DEA Shut Down Their Pain Doctor

The Vaccine Confidence Project

Throughout the world confidence in the Covid vaccine varies

State of Vaccine Confidence in the EU (2022)

State of Vaccine Confidence in the EU (2022) by Country

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Vaccine confidence among the public and healthcare professionals is high across most populations, with some exceptions and caveats. Between 2018 and 2020, there was a large increase in public perception towards vaccines across the EU, particularly towards the seasonal influenza vaccine. Many of these 2020 gains have since been reversed. Perceptions towards the importance, safety, and effectiveness of vaccines have declined across the EU between 2020 and 2022. Across the EU, the view that vaccines are safe remains higher than 2018 levels. Yet, EU-wide changes in public perceptions towards the importance and safety of vaccines shows that strong vaccine-dependence and variability in vaccine confidence exist between countries and within sociodemographic characteristics. 

An evaluation into the differences in public confidence between over 65-year-olds and 18-34-year-olds reveals key insights into an increasing ‘vaccine confidence gap’, which needs to be addressed. The difference in vaccine confidence between 65-year-olds and 18-34-year-olds appears to be widening over time across many EU member states, with 18-34-year-olds becoming less confident between 2018 and 2022.

Vaccine confidence among healthcare professionals remains high in 2022 Above 90% of HCPs surveyed in all EU member states agree that vaccines are important. 

Above 90% of HCPs surveyed in all EU member states agree that vaccines are safe, except for France, Greece, and Austria. 

Healthcare professionals across the EU are highly likely to recommend the MMR, seasonal 

influenza, and COVID-19 vaccines to patients, though likelihood to recommend the HPV vaccine shows high variability between countries.

HCPs likelihood to recommend seasonal influenza and COVID-19 vaccines to pregnant women are generally lower than their likelihood to recommend these vaccines to other patients 

Variability in vaccine confidence exists between countries, among vaccination types, and within sociodemographic characteristics.

The age “gap” in confidence is widening between younger and older age groups   

Between 2018 and 2022, there is increasing polarisation between older and younger age groups in terms of perceptions of vaccines with over 65s becoming more confident and 18-34- year-olds growing less confident.

The seasonal influenza vaccine is the only vaccination where an inverse of this trend can be seen, where the gap between older and younger age groups is narrowing.

Research Feed — The Vaccine Confidence Project