Leana Wen likes to say: “Public health saved your life today. You just don’t know it.” Join the conversation as she describes her experience on the frontlines of this critical—and often invisible—field.
HEALTH TRAIN EXPRESS Mission: To promulgate health education across the internet: Follow or subscribe to Health Train Express as well as Digital Health Space for all the updates for health policy, reform, public health issues. Health Train Express is published several times a week.Subscribe and receive an email alert each time it is published. Health Train Express has been published since 2006.
Saturday, February 19, 2022
Tuesday, February 15, 2022
FAKE NEWS ? Psilocybin treatment for major depression effective for up to a year for most patients - ScienceBlog.com
DISCLAIMER:
This information is neither a recommendation nor advice for treatment. The reader is cautioned to consult with their personal physician prior to using psilocybin for the treatment of any medical or psychiatric condition.
For readers who wish to dive deeper into the subject, read this
Psilocybin is not an FDA approved drug
Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients.
A compound found in so-called magic mushrooms, psilocybin produces visual and auditory hallucinations and profound changes in consciousness over a few hours after ingestion. In 2016, Johns Hopkins Medicine researchers first reported that treatment with psilocybin under psychologically supported conditions significantly relieved existential anxiety and depression in people with a life-threatening cancer diagnosis.A report on the new study was published on Feb. 15, 2022 in the Journal of Psychopharmacology.
The study was done under carefully controlled scientific studies by professional monitors who sat side-by-side with the patient.
Magic Mushrooms have been used for many decades by drug users. It is a powerful psychedelic drug produced by many different fungi, and ingested orally. Like LSD it has been proposed for treatment (Timothy Leary). Leary earned a PhD at U.C. Berkeley and was a psychologist at Harvard University and famous for a speech given "Turn up, turn in, and turn out ".
John Lennon and Yoko Ono were patrons of Leary, Lennon composed the song "Come Together" after meeting Leary.
L-R John Lennon, Timothy Leary, Yoko Ono
Johns Hopkins is one of the sites of a national multisite randomized, placebo-controlled trial of psilocybin for major depressive disorder.
The study was supported by philanthropic donors The Steven and Alexandra Cohen Foundation, Tim Ferriss, Matt Mullenweg, Craig Nerenberg, Blake Mycoskie, and Dave Morin; as well as by grants from the Riverstyx Foundation and the National Institute on Drug Abuse (T32DA007209, R01DA003889, K23DA035915).
Thursday, February 10, 2022
It isn't easy being green
"It isn't easy being green." Kermit, the frog
Why are some potato chips green? are some potato chips green?
This is how poisonous green crisps are - and why you still find them in your packetFew people will happily eat the green crisp - but here's the amount you'd have to eat to get ill, and what causes them.
Why are some potato chips green? — Tasting Table
Wednesday, February 9, 2022
Sunlight: Optimize Health and Immunity (Light Therapy and Melatonin)
Melatonin acts in many ways to maintain your health. Most of you use it to help fall asleep, however, it has many important other functions to maintain good health. Melatonin is produced in the pineal gland. There are receptors (ipRGCs) in the eye, intrinsically photosensitive retinal ganglion cells that are sensitive to infrared radiation. These retinal photoreceptors (nonvisual) send signals to the pineal gland which suppresses melatonin release.
There is another source for melatonin production, mitochondrion. Melatonin is produced as part of the mitochondrial oxidative chemistry. Melatonin serves to ' cool down' mitochondrial overheating. This pathway for NIR penetrates the skin and enters mitochondria stimulating melatonin release. Thus there are two separate paths for melatonin, 1.pineal gland 2. intracellular mitochondria.
Sunlight: Optimize Health and Immunity (Light Therapy and Melatonin)
Melatonin and the circadian rhythm play a pivotal role in rest, good health, and eliminating oxidative stress. The video by Medcram (Robert Seheult, M.D., UC Riverside School of Medicine
https://doi.org/10.32794/mr11250016
Monday, February 7, 2022
Goldie Hawn Opens Up About Her Childhood Depression & The Importance of ...
The Covid pandemic may be somewhat better, however, our children are still in recovery mode. The best way to deal with childhood depression is to discuss it with them. Ask how they are feeling.
Goldie Hawn developed "Mind Up", a course for children about mental health.. This course is inexpensive and gives guidance and a curriculum for assisting children develop mental health.
Sunday, February 6, 2022
Hobby Tool | Find New Activities to Replace Gaming
In the world of addiction therapy, most psychiatrists treat addiction as an obsessive-compulsive personality disorder. OCD can be difficult to treat, and there are some psychoactive drugs now available to treat OCD. Many of these drugs are SSRI'S and carry significant side effects. The use of SSRI drugs in children also carry other significant side effects
Most parents and physicians prefer to not put children or teens on psychoactive drugs, except in the most severe types of depression, when other options fail. While it is challenging to treat OCD it is possible to transfer their form of gaming addiction to other forms of entertainment, or activity. Teens often have sports activities, tennis, running, baseball or football. The neurochemical response to any addiction is a release of endorphins, running in particular. ( Endorphins, dopamine and serotonin are all related to mood elevation. What is the difference between endorphins and dopamine in your brain? While endorphins are neurotransmitters that help you to cope with pain and stress, dopamine is a mood-boosting neurotransmitter that is released after you reach a goal.)
In this way, dopamine is involved in the reward circuit in your brain and helps to motivate you toward tasks (in contrast, low dopamine would also be de-motivating). Higher endorphins can actually lead to higher dopamine production; in this way, endorphins and dopamine are not mutually exclusive but are actually connected in the system that promotes action toward rewards and the good feelings that result.
In other words, you might feel motivated to participate in a marathon because of your dopamine reward system, which is further reinforced by the endorphins that are released during the actual act of participating in the race. In this way, endorphins are the quicker-acting "feelings" while dopamine is the longer-acting afterglow.
Need new activities to replace gaming? Use our hobby tool. Contains 70+ different ideas with 12 filters from which to select new hobbies
Our most recent edition of Health Train Express discussed Behavioral addiction to online social networking and its association with emotion regulation deficits.
Most parents and others recognize that their children are missing from the dinner table or refuse to participate in normal family activities. They linger far into the night with their bedroom doors closed. In some cases, they may be gaming alone or have a virtual social network to play games with friends they know already or have never met from other countries.
In previous generations, many parents wanted to know who their children hang out with. Today, such is not the case. Parents rarely know with whom their children socialize. Back in the day mothers would insist on meeting the 'friends' and also their parental units to either give approval or suggest they find other friends.
Many parents from prior generation(s) are internet incompetent, however, today's young parents grew up in the internet age and are knowledgeable about its pitfalls.
Parent Guides from ConnectSafely
Is a handy guide for parents with information about many internet gaming sites, such as Snapchat, Instagram, Roblox, Tiktok, Amazon Parent Dashboard, Amazon Fire TV. Discord, Cyberbullying Messenger, Messenger for Kids, developed by Facebook allows parents the ability to control their kid's messenger contracts.
One important tool is Google Family Link which allows monitoring and permissions remotely from a parent's smartphone or computer. It requires an app on the child's device and the parent's device. Other software such as parental blocking on a home Wi-Fi router can help as well, but many social networks and games can be accessed via cell phone without internet.
Top Questions from Parents
1. What is Family Link?
Family Link is an app from Google that allows you to set-up, manage and monitor a Google account and Android device for your child so even young children can take advantage of the benefits of having a smartphone or tablet.
2. What does Family Link do?
The app gives you the ability to manage what apps your kids can use and when they can use them, what websites they can visit, and when they can use the device. Parents can set a device’s “bedtime” so that it can’t be used for anything except phone calls during specific hours of the day or night.
3. What do I need to set up a Family Link account?
You need a compatible Android smartphone or tablet for your child (find details on this webpage) and either an Android or Apple phone or tablet for yourself to manage your child’s account. You can manage some of your child’s account settings from a web browser, but need an Android device for some features and settings. You’ll also need to be in the U.S., and have your own Google account.
4. What are the minimum and maximum ages of kids who can use Family Link?
The app doesn’t have a minimum age. It’s up to parents to decide when their child is ready to have a managed smartphone. For Family Link users, Google will notify both the parent and the child before the child’s 13th birthday, “to encourage a family conversation around when the child will be ready to take control over their own account and device.” The child has the option to transition to a regular account or remain under parent management up until their 18th birthday.
5. Why should my family use Family Link?
There are a great many benefits to smartphones and tablets, even for very young children. We can’t list them all, but they include the ability to make calls and send and receive texts and emails with family members, the ability to use educational apps or games, the ability to take and share pictures, track health and fitness data, and much more. Also, it’s possible to configure your child’s phone so that it securely reports its location to you, which means you know where the phone is and, if the phone is with your child, where the child is as well. Of course, you could give your child a device without Family Link but then you wouldn’t have the ability to manage the apps they use, the sites they visit, and the times they’re using it, and be able to monitor how your child is using the phone. Family Link helps your child learn how to responsibly use their device while giving parents extra peace of mind.
6. Who can manage my child’s account?
By default, it’s just the person who sets up the account but the family manager can add another family member to serve as a second parent who can manage and monitor the child’s device.
7. What should I say to my child before installing Family Link?
It is always a good idea to have a discussion with your child before allowing them to use a device and before using any monitoring or device management tool. Remind your child about their responsibility to use the device appropriately and to take good care of the device. Explain any family ground rules and policies, and talk with them about the features in Family Link so they understand what information you can monitor and how you will be able to manage what they can do with their device. If you elect to limit the apps and sites they use, explain how they can ask permission if they come across an app or site that they would like you to add.
Authors notes:
The situation is not hopeless, and there are credible solutions to protect children from exploitation. As the reader can see Facebook has "Facebook for Kids", Tiktok has Privacy settings,
Hobby Tool | Find New Activities to Replace Gaming
Thursday, February 3, 2022
META and SNAPCHAT are sued by parent of 11 year old who committed suicide.
Are Meta Platforms Inc. and Snap Inc. to blame for the suicide of an 11-year-old who suffered from depression and sleep deprivation after becoming addicted to Instagram and Snapchat, the girl’s mother alleged in a lawsuit.
If the parent prevails in this case it would be a huge precedent-setting case, not dissimilar to the Perdue opioid settlement for opioids.
The case will require evidence from experts in addictive behavior. Some neuroscientists have published evidence (Andrew Doan, MD, Ph.D.). Dr. Doan is an ophthalmologist, whose Ph.D. thesis included addictive behavior in video gamers. He also authored "Hooked on Games"
The complaint appears to be the first of its kind against Meta, formerly known as Facebook Inc., said attorney Matthew Bergman, who founded Social Media Victims Law Center in Seattle and represents Rodriguez’s mother.
“There is a mental health epidemic among American teens,” Bergman said. He added that he anticipates a significant number of similar cases will be filed after a former Facebook employee turned whistle-blower testified in Congress in October that the company knew about, but didn’t disclose, the harmful impacts of services like Instagram.
This is unacceptable behavior behind the curtain of 'freedom of speech' and unaccountability. Despite Meta and Snapchat's disavowal of responsibility, there is a growing concern about their effect on morals. Young children's perception of reality becomes confused with virtual reality during their formative years.
Unguided children self treat their anxiety and fear on the internet.
What You’ll Learn
The study finds that social media, sex, and nicotine might be equally addictive
Social media addiction and substance abuse
Facebook addiction linked to brain reward and gratification
Contributing Factors to Social Media or Social Networking Addiction
Dangers of teen social media addiction
Signs of social media addiction in teens
Limiting teens’ social media use to prevent addiction
Internet Gaming Disorder—was included in Section 3 of the diagnostic and Statistical Manual of Mental Disorders (DSM–5)
If you are concerned about social media addiction and/or video gaming addiction Social Media Victims Law Center in Seattle, Washington is an excellent starting point.
Other References:
Tuesday, February 1, 2022
Potpourri of Healthy Eating Habits
Slowing the Aging Process: Two Blood Proteins Could Be Key to a Long and Healthy Life
Two blood proteins have been shown by scientists to influence how long and healthy a life we live, research suggests.
Developing drugs that target these proteins could be one way of slowing the aging process, according to the largest genetic study of aging.
As we age, our bodies begin to decline after we reach adulthood, which results in age-related diseases and death. This latest research investigates which proteins could influence the aging process.
Many complex and related factors determine the rate at which we age and die, and these include genetics, lifestyle, environment, and chance. The study sheds light on the part proteins play in this process.
Some people naturally have higher or lower levels of certain proteins because of the DNA they inherit from their parents. These protein levels can, in turn, affect a person’s health.
University of Edinburgh researchers combined the results of six large genetic studies into human aging – each containing genetic information on hundreds of thousands of people,
Among 857 proteins studied, researchers identified two that had significant negative effects across various aging measures.
People who inherited DNA that causes raised levels of these proteins were frailer, had poorer self-rated health, and were less likely to live an exceptionally long life than those who did not.
The first protein, called apolipoprotein(a) (LPA), is made in the liver and thought to play a role in clotting. High levels of LPA can increase the risk of atherosclerosis – a condition in which arteries become clogged with fatty substances. Heart disease and stroke are possible outcomes.
The second protein, vascular cell adhesion molecule 1 (VCAM1), is primarily found on the surfaces of endothelial cells – a single-cell layer that lines blood vessels. The protein controls vessels’ expansion and retraction – and function in blood clotting and the immune response.
Levels of VCAM 1 increase when the body sends signals to indicate it has detected an infection, VCAM1 then allows immune cells to cross the endothelial layer, as seen for people who have naturally low levels of these proteins.
The researchers say that drugs used to treat diseases by reducing levels of LPA and VCAM1 could have the added benefit of improving quality and length of life.
One such example is a clinical trial that is testing a drug to lower LPA as a way of reducing the risk of heart disease.
There are currently no clinical trials involving VCAM1, but studies in mice have shown how antibodies lowering this protein’s level improved cognition during old age.
The findings have been published in the journal Nature Aging.
Dr. Paul Timmers, lead researcher at the MRC Human Genetics Unit at the University of Edinburgh, said: “The identification of these two key proteins could help extend the healthy years of life. Drugs that lower these protein levels in our blood could allow the average person to live as healthy and as long as individuals who have won the genetic lottery and are born with genetically low LPA and VCAM1 levels.”
Professor Jim Wilson, Chair of Human Genetics at the University of Edinburgh’s Usher Institute, said: “This study showcases the power of modern genetics to identify two potential targets for future drugs to extend lifespan.”
Reference: “Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging” by Paul R. H. J. Timmers, Evgeny S. Tiys, Saori Sakaue, Masato Akiyama, Tuomo T. J. Kiiskinen, Wei Zhou, Shih-Jen Hwang, Chen Yao, Biobank Japan Project, FinnGen, Joris Deelen, Daniel Levy, Andrea Ganna, Yoichiro Kamatani, Yukinori Okada, Peter K. Joshi, James F. Wilson and Yakov A. Tsepilov, 20 January 2022, Nature Aging.
DOI: 10.1038/s43587-021-00159-8
Drinking This Before Bed May Help You Sleep (And It's Not Warm Milk)
One of the most important ways to ensure you have a great day is to get a good night's rest. Yet one-third of Americans report they get less than the recommended amount of sleep, says the Centers for Disease Control and Prevention (CDC). This can not only leave you feeling groggy—which leads to a higher incidence of accidents and motor vehicle crashes— but can also cause serious health issues down the line, including an increased likelihood of heart disease, obesity, depression, and diabetes. "Getting enough sleep is not a luxury—it is something people need for good health," the CDC warns.
NyQuil Cold & Flu Medicine
Excedrin Migraine
Excedrin contains caffeine, which is obviously a stimulant that makes your brain more alert,
Sudafed
One key ingredient in Sudafed for relieving nasal congestion is pseudoephedrine. "Pseudoephedrine will often make it difficult for people to both go to sleep and stay asleep," says Kerr.
Benadryl
This medicine forces the brain to spend more time in the lighter stages of sleep. This means reduced sleep quality. And when you wake up after eight hours of slumber, you will be likely to feel like you've had only five."
Beta-Blockers
A few examples include Lopressor, Toprol, Tenormin, and Betapace. But they've got a long history of disturbing sleep. "Beta-blockers may cause nightmares and nighttime waking. By slowing the secretion of melatonin, the body's hormone devoted to regulating your internal clock, beta-blockers have been known to promote chronic insomnia.
If you need to take beta-blockers, consider taking melatonin supplements.
And finally here are.
50 Tips for Sleeping Better Tonight, According to Experts
Expert Newsletters - Cardio Prevention, Covid 19
Joel Kahn M.D. Interventional Cardiologist
A weekly collection focused on cardio prevention
Joel Kahn, MD, FACC of Detroit, Michigan, is a practicing cardiologist, and a Clinical Professor of Medicine at Wayne State University School of Medicine. He graduated Summa Cum Laude from the University of Michigan Medical School. Known as "America’s Healthy Heart Doc", Dr. Kahn has triple board certification in Internal Medicine, Cardiovascular Medicine, and Interventional Cardiology. He was the first physician in the world to certify in Metabolic Cardiology with A4M/MMI and the University of South Florida. He founded the Kahn Center for Cardiac Longevity in Bingham Farms, MI. Dr. Kahn has authored scores of publications in his field including articles, book chapters and monographs. He writes health articles and has 6 books in publication including Your Whole Heart Solution, Dead Execs Don’t Get Bonuses and The Plant-Based Solution, and Lipoprotein(a): The Heart’s Silent Killer. He has regular appearances on Dr. Phil, The Doctors Show, Dr. Oz, Larry King Now, Joe Rogan Experience, and with Bassem Yousef. He has been awarded a Health Hero award from Detroit Crain’s Business. He serves as medical director of the largest plant support group in the USA, www.pbnsg.org. Dr. Kahn can be found at www.drjoelkahn.com.
The Red Wine Study Many Are Raising Their Glasses Too
An analysis of the relationship of red and white wine drinking and C19 infection shows an association with benefits to raising a glass? Caution all but at least hypothesis-generating. Do you know your Lp(a) level, your patient's levels? The prognostic power of Lp(a) suggests you should as I check in 100% of my clinic visits. CIMT is a powerful tool I use routinely to track plaque and it is valid in children too. Broccoli, aging, cherry juice, and dietary epigenetics finish the list with a bowed head and a walking meditation in memory of Thich Nhat Nahn.
The study found that those who drank one to two glasses of red wine per day had between a 10 and 17 percent lower risk of getting Covid-19 when compared with teetotalers. White wine drinkers in the study who drank between one and four glasses a week reduced their risk of contracting Covid-19 by 7 to 8 percent.
Meanwhile, beer and cider drinkers increased their risk of contracting the virus by 28 percent over non-drinkers, regardless of the amount they consumed. Those who drink five or more hard alcohol drinks a week also increased their risk of infection. Heavy drinkers of all types of alcohol also had an increased risk.
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