Blood test can effectively rule out breast cancer, regardless of breast density:

 An important advancement in breast cancer detection in women with dense breast imaging.

Dense breast tissue: What it means to have dense breasts

Dense breast tissue is detected on a mammogram. Additional imaging tests are sometimes recommended for women with dense breasts.

By Mayo Clinic Staff

If a recent mammogram showed you have dense breast tissue, you may wonder what this means for your breast cancer risk. Doctors know dense breast tissue makes breast cancer screening more difficult and it may increase the risk of breast cancer.

In the United States, laws require doctors in some states to inform women when mammograms show they have dense breasts. But just what women should do in response isn't clear.

What is dense breast tissue?

Dense breast tissue refers to the appearance of breast tissue on a mammogram. It's a normal and common finding.

Breast tissue is composed of milk glands, milk ducts and supportive tissue (dense breast tissue), and fatty tissue (nondense breast tissue). When viewed on a mammogram, women with dense breasts have more dense tissue than fatty tissue.

On a mammogram, nondense breast tissue appears dark and transparent. Dense breast tissue appears as a solid white area on a mammogram, which makes it difficult to see through.

Ref:

Breast density does not impact the ability of Videssa® Breast to detect breast cancer in women under age 50

This information is intended only as general, and patients must confer with their physician for interpretation of images and followup testing and/or treamtent

Blood test can effectively rule out breast cancer, regardless of breast density: With over a 99 percent negative predictive value, a liquid biopsy test can help clinicians manage difficult-to-diagnose dense breast patients -- ScienceDaily