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Tuesday, October 11, 2022
APIC urges members to disregard new CDC masking guidelines
Long COVID Experts: U.S. Government Needs to Do More | Time
Long COVID Experts and Advocates Say the Government Is Ignoring 'the Greatest Mass-Disabling Event in Human History'
Sunday, October 9, 2022
Prosopagnosia (face blindness) Do you suffer from this? Brad Pitt has it
People who are diagnosed with prosopagnosia often fall into one of two categories: either they are born with it or they acquire it.
Prosopagnosia is not related to memory problems, vision loss, or learning disabilities, but it's sometimes associated with other developmental disorders, such as autism spectrum disorder, Turner syndrome, and Williams syndrome. However, estimations reveal that as many as one in every 50 people may struggle with some lifetime form of the disorder, and experts hypothesize that it may run in families.
According to Blum, research “suggests that congenital, or lifelong, prosopagnosia is less prevalent.”
According to Andrey Stojic, director of general neurology at the Cleveland Clinic, children born with the illness “don’t seem to have any visible structural abnormality” in the brain.
Notably, doctors don’t fully understand what causes congenital prosopagnosia because there aren’t any obvious brain lesions in persons who have it.
In contrast, people who develop prosopagnosia later in life may have brain abnormalities brought on by a trauma or head injury.
According to Bonakdarpour, individuals can also develop prosopagnosia while dealing with Alzheimer’s illness or following a stroke.
What therapies are available for prosopagnosia?
Borna Bonakdarpour, MD
Assistant Professor of Neurology (Behavioral Neurology
Prosopagnosia is now untreatable, according to Bonakdarpour. The problem can be treated, though.
People who have the syndrome frequently attempt to distinguish between people by focusing on physical characteristics like hair color, gait, or voice.
Usually, a set of tests that measure a person’s memory and face recognition help neurologists make the diagnosis.
As doctors frequently take care to ensure that a patient’s face blindness is not an indication of a more extensive degenerative neurological disorder, Blum adds, “it can be a drawn-out process.”
It’s noteworthy that many people with the illness, like Pitt, won’t get an official diagnosis.
Many of the difficulties he’s discussing and the issues he has are not unusual for people to go through them, according to Stojic.
He continued, “It may be relatively crippling for folks. “Others find it difficult to comprehend,”
Thursday, October 6, 2022
Worldwide Directory of Pregnancy Help
Listening to Black Californians: How the Health Care System Undermines Their Pursuit of Good Health - California Health Care Foundation
California, home to the most culturally diverse population in the country and the fifth-largest Black population of any state, has a major opportunity to be a leader in health equity. But glaring racial and ethnic inequities pervade its health care system, from insufficient access to worse health outcomes to excess mortality.
Black residents have the shortest life expectancy (75 years) at birth of any racial/ethnic group, six years shorter than the state average. Black Californians have the highest death rates from breast, cervical, colorectal, lung, and prostate cancers. Black birthing people experience the highest rates of prenatal and postpartum depression, preterm births, low birthweight births, and pregnancy-related mortality. And Black infants have the highest mortality rates.
As part of its commitment to ending health inequities, CHCF commissioned Listening to Black Californians, a three-phase qualitative and quantitative study to understand the health and health care experiences of Black Californians. The research is being conducted by EVITARUS, a Black-owned public opinion research firm in Los Angeles. An advisory group composed of academics, policymakers, providers, and community advocates is guiding the study.
This report describes the results of Phase I of the Listening to Black Californians study. In this phase, EVITARUS conducted individual, hour-long interviews with 100 Black Californians from June to August 2021 to understand their views on health and well-being, their perceptions of discrimination and bias in the health care system, and their views on what a quality health care system looks like. Each story provided unique insights. Still, taken as a whole, the stories revealed many similarities in how Black Californians view health and how they experience health care.
Key findings include:
- Respondents held a holistic view of health and prioritized it in their everyday lives.
- Experiences with racism in health care were widespread and negatively impacted participants’ health.
- Participants envisioned high-quality health care as patient-centered and proactive.
The complete report is available under Document Downloads.
In Their Own Words: Black Californians on Racism and Health Care — Executive Summary (PDF)
Findings suggest COVID-19 rebound not caused by impaired immune response | National Institutes of Health (NIH)
Monday, September 26, 2022
Psychedelics Stocks to Watch (Updated 2022)
The small-cap market has been invaded by a flurry of psychedelics stocks to watch thanks to new company launches. Investors now have a variety of options for taking a run in the shroom stocks space.
In an effort to expand the capabilities of the medical field, companies are starting to investigate the potential of psychedelic medicines and are looking to raise capital in the public market.
While this industry is still in its early stages, the promising potential of psychedelic medicine drug products has attracted the interest of savvy investors eager for an emerging investment opportunity.
A shroom boom is in the works, led by encouraging results from psychedelic medicine treatments for various issues associated with mental health, and in connection to potential global law changes.
Here the Investing News Network presents a current list of psychedelics stocks to watch. The following stocks are all listed on public stock exchanges and are arranged alphabetically.
Aion Therapeutic (CSE:AION,OTC Pink:ANTCF)
Company Profile
Aion Therapeutic is in the business of research and development, treatment, data mining and state-of-the-art artificial intelligence techniques. It is focused on the development of combinatorial pharmaceuticals, nutraceuticals and cosmeceuticals utilizing compounds from cannabis, psychedelic mushrooms, fungi, natural psychedelic formulations and other medicinal plants in a legal environment for this type of discovery.
Albert Labs (CSE:ABRT)
Press Releases
Company Profile
Albert Labs is Vancouver-based research and drug-development company focused on improving patient access to innovative mental health medications. The company is presently developing a natural psilocybin-based medication for patients with cancer-related distress.
Algernon Pharmaceuticals (CSE:AGN,OTCQB:AGNPF)
Company Profile
Algernon Pharmaceuticals is a clinical-stage drug-development company focused on the disease areas of stroke, idiopathic pulmonary fibrosis and chronic cough.
Allied (OTCQB:ALID)
Company Profile
Allied has both cannabinoid and psilocybin products in the pharmaceutical development track, and is seeking pharma drug indications for depression, anxiety and post-traumatic stress disorder.
ATAI Life Sciences (NASDAQ:ATAI)
Company Profile
ATAI Life Sciences is a clinical-stage biopharma company aiming to transform mental health disorder treatment.
Monday, September 19, 2022
Sunday, September 18, 2022
To boost or not to boost - by Eric Topol - Ground Truths
The reluctance for Americans to get a booster shot has been striking. The United States currently ranks 73rd among countries for its uptake of boosters at 33% of its population. All peer, rich countries around the world are at least double that rate. Countries ranking above the US now include Rwanda, Uzbekistan, Iran, Honduras, and Azerbaijan. Seemingly, you’d have to work very hard to show up this poorly as the country that first validated the vaccines, manufactures them, and has had such a surfeit supply that it has >50 million shots it can’t get anyone to take. Nonetheless, it has maintained optimism and purchased 171 million new Omicron BA.5 variant bivalent shots.
So why is the rate of immunization so low in the United States? It is not about science. Eric Topol M.D. is a well-respected authority. Precision Medicine is touting how we need another booster shot. It is also not a political issue. Americans no longer have faith in government recommendations. During the last several decades the U.S. government made many poor choices, including severe restrictions, social distancing, personal protective equipment, and shutting down the economy, as well as promoting major wars in Iraq and Afghanistan.
In other countries that may be less developed, people accept government decisions, not knowing the details about vaccines. %10%1
Our current rate of inflation (about 10%) is largely due to the stimulus packages. That was money we printed, for which there is no real backing.
On the one hand, according to Topol, there is incontrovertible evidence for the benefit of a booster.
Very strong evidence supporting boosters dates back to October 2021, when the results of the only large (~10,000 participants) (1st) booster randomized trial were released and later published, with a 95% reduction of symptomatic infections across all age groups, through the Delta wave, durable at that level for at least 4 months. There were no safety concerns or myocarditis. The efficacy level was fully restored to the original randomized trial (95%) reports in November 2020.
The right question
Boosters provide substantive and unequivocal benefits for protection from severe Covid and are likely to help, to at less some degree, reduce Long Covid, and certainly have some early (2 months) effects for reducing infection and transmission. We don’t know yet if the BA.5 bivalent booster is any better than the BA.1 or the original booster. Based on the evolution of the virus through Omicron and its subvariants, it appears unlikely the new vaccine will have a major or important impact on reducing infection or transmission (we got a hint of that from the new BA.1 NEJM study above). There’s ample evidence from multiple studies that mucosal IgA antibodies are what will be needed to help block infections and transmission, such as this NEJM new report with 60-80% reduction of breakthrough infections (and reduced viral load, higher Ct, Tables below) as a function of mucosal IgA antibodies, not related to IgG antibodies. While they were formed in some health care workers as a response to vaccination and or infection, there is a way to induce them via nasal or oral vaccines. The durability of this effect isn’t yet known, but it would be far easier to take a nasal spray repetitively, with the expectation of much fewer side effects, than shots. Certainly encouraging data from CanSino’s newly approved inhaled vaccine vs Omicron is a solid precursor for the many programs that are in advanced clinical trials.
The right question is about the future. We can’t go on getting boosters every 4 to 6 months and the premise of an “annual” shot is that the virus exhibits seasonality like flu, which certainly isn’t the case.
Economics play a large role in who gets vaccines. In poor countries, it is often not available. In developed countries including the U.S. that is not a limiting factor.
The truth lies somewhere in the statistics which can be read below.
This reminds me of what a professor told me a long time ago. Beware! Statistics often lie!
To boost or not to boost - by Eric Topol - Ground Truths: Should that be the question?
The Truth About the Flu Shot
What’s in the Regular Flu Shot?
- Egg protein and avian contaminant viruses
- Thimerosal (mercury): in multi-dose vials
- Polysorbate 80:allergen; infertility in mice
- Formaldehyde: carcinogen
- Triton X100: detergent
- Sucrose: table sugar
- Resin: known allergen
- Gentamycin: antibiotic
- Gelatin: known allergen
Not in adults: In a review of 48 reports (more than 66,000 adults), “Vaccination of healthy adults only reduced risk of influenza by 6% and reduced the number of missed work days by less than one day (0.16) days. It did not change the number of people needing to go to hospital or take time off work.”
Not in the Elderly: In a review of 64 studies over 98 flu seasons of elderly living in nursing homes, flu shots were non-significant for preventing the flu. For elderly living in the community, vaccines were not (significantly) effective against influenza, ILI or pneumonia.