Covid 19 vaccine was not a miracle...read more

Many politicians claim the vaccine is a miracle, however like magic the truth is in the science.

History of  CIRM

Over 15 years ago, in California, proposition 71 was presented to the voters to create the California Institute of Regenerative Medicine and funded it with a 3 billion dollar bond issue. This occurred when then President George Bush placed a ban on harvesting human fetal tissue for stem cell research. The reason was the hot topics of right to life and faith issues.  It was a political issue. 

The CIRM allowed stem cell research to continue using adult stem cells in lieu of fetal stem cells. Certain adult organs contained primitive and only partially differentiated stem cells. Tissues that rapidly multiply such as bone marrow and skin were likely candidates.  Fortunately, this hypothesis was true. 

This formed the foundation for the Moderna and Pfizer-Bionet covid 19 vaccines. CIRM  is an interesting story in itself and worth reading about. 

Had CIRM not been formed there would have been other significant delays in the basic science of stem cells.

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Cancer patients and Covid 19 Vaccinations.

As two new COVID-19 vaccines become more widely available, patients with cancer and cancer survivors may wonder if it's safe to be vaccinated.

"Because cancer patients and survivors are at higher risk for severe effects from COVID-19 infection, we recommend they get vaccinated as soon as they can," says Robert McWilliams, M.D., a medical oncologist at Mayo Clinic. "Patients who are immunosuppressed due to active cancer treatment may not get the same effective response as someone without immune compromise, but it should still be safe for them to receive the vaccine."

There is no definitive data on the efficacy of the COVID-19 vaccines from Pfizer/BioNTech and Moderna in patients with cancer or cancer survivors. "However, the few patients with cancer who were studied as part of the clinical trials leading to the approval of these vaccines did not experience any unique side effects," says Joleen Hubbard, M.D., a medical oncologist at Mayo Clinic.

The good news for patients with cancer and cancer survivors is that the Pfizer/BioNTech and Moderna COVID-19 vaccines are not live virus vaccines. That makes them less likely to cause side effects in immunosuppressed patients. "Both vaccines are mRNA (messenger RNA) vaccines, which means they teach our bodies how to make a protein that will trigger an immune response without the use of a live virus that causes COVID-19," says Dr. Hubbard. "Once triggered by the protein, our immune system makes antibodies to protect us if we are exposed to the virus."

Now that the vaccine is becoming available in the United States, expect to see more cases of side effects, however, the incidence rate remains the same.

Average daily case rate of Covid 19 positive cases.  Many of these patients have mild, moderate, or no symptoms.

Moderna Vaccine

Pfizer-Bionet

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The Relationship Between Alzheimer’s Disease and Diabetes

Society for Neuroscience - Inside Neuroscience: The Relationship Between Alzheimer’s Disease and Diabetes

Inside Neuroscience: The Relationship Between Alzheimer’s Disease and Diabetes

Regions of the “social brain,” including the medial prefrontal cortex (mPFC), temporoparietal junction (TPJ), posterior superior temporal sulcus (pSTS), amygdala, and anterior cingulate cortex (ACC). Source: Sarah Jayne Blackmore, Nature Reviews Neuroscience 2008.

Alzheimer’s disease is the most common form of dementia, affecting over 50 million people worldwide, with rates expected to triple in the next 30 years. The disease is characterized by aggregates of amyloid-beta outside neurons and tangles of hyperphosphorylated tau within neurons. More recently, evidence suggests a disturbance in glucose metabolism in the Alzheimer’s brain as well, although whether this is a cause or symptom of the disease remains unclear. Type 2 diabetes — in which blood glucose levels are elevated — increases the risk for Alzheimer’s disease about two-fold.

A better understanding of the relationship between these two diseases may yield novel therapies. At the Neuroscience 2019 press conference “Untangling the Link Between Diabetes and Alzheimer’s Disease,” researchers shared new insights into how glucose metabolism problems and Alzheimer’s pathology could be related, disrupted, and potentially fixed.

Test your knowledge about Viruses Quiz gone viral - Cold Spring Harbor Laboratory

Coronavirus (COVID-19) Self-Checker

John. Hopkins is one of the best sources for Covid 19.  Beginning in January 2020 JHU has reported daily on the extent of the pandemic with an interactive global map detailing the number of cases worldwide by country.

Covid Dashboard

COVID-19 has caused a sea-change for business, social activities, health care, education, and government. There have been few other cataclysmic events in our history such as Pearl Harbor, Nine-eleven, and the Civil War.  It unleashed public outcry for police reform, justice, and too many others to list here.

In order to understand what Covid-19 is all about we are going to point readers to credible references.

Covid-19 is the first recent pandemic to affect the globe. Several other epidemics such as Ebola, Zika, SARS and H1N1 influenza pale in the extent of global involvement.  Ebola, Zika was a regional disease that did not extend to a pandemic.

This brief discussion is expanded by clicking here